Found 13 matching trials
SCRT + Chemo Targeted Immuno-neoadjuvant Therapy for High-risk pMMR/MSS RC PHASE3 To explore the efficacy and safety of an intensified treatment regimen cons...
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Sixth Affiliated Hospital, Sun Yat-sen University
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A Study on the Efficacy and Safety of Multi-mode Ablation Combined With Systemic Therapy in the Treatment of CRCLM PHASE2 The goal of this study is to evaluate the efficacy and safety of multi-mode...
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Shanghai Sixth People's Hospital
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Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Chinese Participants With Stage IV Colorectal Cancer (MK-3475-C66) PHASE3 In this study, Chinese participants with MSI-H or dMMR advanced colorectal ...
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Active Not Recruiting
Location
Beijing Cancer hospital-Digestive Oncology ( Site 0001)
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The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal Cancer PHASE2 The study is a prospective, single-center, single-arm, two-cohort, phase II...
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Fudan University Shanghai Cancer Center
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First-Line Treatment Induced With mFOLFOX6 and HLX04 Regimen, Following Combined With Serplulimab in MSS Initially Unresectable Metastatic Colorectal Cancer PHASE2 This is a prospective, multi-center, randomized controlled clinical interve...
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Sir Run Run Shao hospital
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A Study of HX008 Compared to Chemotherapy in the First-Line Treatment of Subjects With MSI-H/dMMR Metastatic Colorectal Cancer PHASE3 The main purpose of this study is to compare the clinical benefit, as measu...
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Active Not Recruiting
Location
The First Affiliated Hospital of Bengbu Medical University
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Chemotherapy Plus Bevacizumab and Anti-PD-1 Followed by Induction Therapy of Chemotherapy Plus Bevacizumab PHASE2 Fluorouracil and oxaliplatin-based combined with molecular targeted drugs a...
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Sir Run Run Shao hospital
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SCRT+mFOLFOX6+PD-1 Antibody and Targeted Therapy for High-Risk pMMR/MSS Rectal Cancer PHASE2 To explore the efficacy and safety of short-course radiotherapy combined wi...
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Sixth Affiliated Hospital, Sun Yat-sen University
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An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer. PHASE1 This randomized phase 1b/2 open-label study will evaluate the antitumour ac...
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Arizona Clinical Research Center Inc
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mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC PHASE3 Neoadjuvant immunotherapy has shown promising therapeutic effects in mismat...
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The Sixth Affiliated Hospital, Sun Yat-sen University
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